Research Paper Volume 12, Issue 7 pp 5832—5857

Development of a prognostic index and screening of potential biomarkers based on immunogenomic landscape analysis of colorectal cancer

Figure 3. Protein protein interaction network and GO network of prognosis-related immune genes. (A) Protein-protein interaction network of prognosis-related immune genes, revealing their intrinsic connections. (B) The constructed PPIs in Cytoscape, with the size of the nodes showing the degree of connectivity of the immune genes, reveal the hub genes in the network. (C) Gene ontology network of prognosis-related immune genes. The color shade of the node represents the p-value, darker colors indicate smaller P values. P < 0.05 indicates statistically significant difference.