Research Paper Volume 12, Issue 8 pp 6600—6610

PHTF2 regulates lipids metabolism in gastric cancer

Figure 4. PHTF2-regulated fatty acid metabolism promotes tumorigenic ability of gastric cancer cells in vitro and in vivo. (A) CCK8 assay showed cells viability in the indicated cells. (B) Colony formation assay showed cell growth of the indicated cells. (C) Qualification of the colony formation shown in B (n=3). (D) The representative pictures of dissected tumors from nude mice transplanted with indicated cells. (E) Subcutaneous tumor growth curves of mice in different treatment groups was presented. (F) The average weight of tumors at the time the animals were sacrificed in the indicated groups. (G) Relative mRNA expression pattern of associated gene in tumor tissue acquired from nude mice.