Research Paper Volume 12, Issue 7 pp 6191—6205

Long non-coding RNA TPT1-AS1 promotes angiogenesis and metastasis of colorectal cancer through TPT1-AS1/NF90/VEGFA signaling pathway

Figure 6. Clinical relations between TPT1-AS1 and VEGFA in CRC patients’ tissues. (A) IHC staining was used to detect the VEGFA expression in clinical and xenograft tumor samples. The clinical and xenograft samples were divided into TPT1-AS1 high or low groups by using qRT-PCR. (B) A positive relationship between TPT1-AS1 and VEGFA expression was confirmed in clinical samples by Pearson analysis. (Ci) The Kaplan-Meier analysis was used to show the overall survival of patients in TPT1-AS1 high/low groups. (Cii) The overall survival of patients in indicated TPT1-AS1/VEGFA expression groups.