Research Paper Volume 12, Issue 8 pp 6680—6699

Long intergenic non-protein coding RNA 324 prevents breast cancer progression by modulating miR-10b-5p

Figure 2. Downregulation of LINC00034 expression predicts worse prognosis for patients with breast cancer. (A) qRT-PCR analysis of LINC00324 expression in breast cancer tissues and paired adjecent normal tissues after normalization to GAPDH. (B) qRT-PCR analysis of LINC00324 expression in different TNM stages after normalization to GAPDH. (C) qRT-PCR analysis of LINC00324 expression in MDA-MB-231, MCF-7, and MCF-10A cells, after normalization to GAPDH. (D) Kaplan–Meier analysis for overall survival based on low and high LINC00324 expression levels (the KM Plotter database). All data are shown as means ± SEM. * P < 0.05, ** P < 0.01, *** P < 0.001. Data are from three independent experiments (C).