Aging
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Figure 5
Figure 5.Exercise training inhibited components of FAS-dependent and mitochondrial-dependent apoptotic pathways activation in hippocampus of D-galactose-induced aging rats. (A) The representative protein levels of FAS ligand, activated FAS receptor, FADD, activated Caspase 8. (B) Bad, Cytochrome C, Caspase 9 and (C) Caspase 3 prepared from hippocampal homogenates in the control, exercise, aging and aging with exercise rats were measured by Western blotting analysis (n=3). The protein expression folds were normalized with β-actin. * P <0.05, **P<0.01, ***P<0.001, significant differences from the control group. ##P <0.05, ###P <0.01, ###P<0.001.significant differences from the D-galactose-induced aging group.
Figure 5 — Swimming exercise stimulates IGF1/ PI3K/Akt and AMPK/SIRT1/PGC1&#x3B1; survival signaling to suppress apoptosis and inflammation in aging hippocampus | Aging