Research Paper Volume 12, Issue 8 pp 6891—6903

Hypoxia-induced let-7f-5p/TARBP2 feedback loop regulates osteosarcoma cell proliferation and invasion by inhibiting the Wnt signaling pathway

Figure 1. (A) let-7f-5p expression was decreased in osteosarcoma (OS) cell lines. qRT-PCR was used to evaluate the endogenous levels of let-7f-5p in hFOB cells and HOS, U2OS, and Saos OS cell lines. (B) and (C) qRT-PCR was used to quantitate the expression of let-7f-5p following transfection with the let-7f-5p mimic or inhibitor in Saos cells.