Figure 2. Transcriptome analysis for normal and delayed cutaneous wound tissue. (A, B) Cluster analysis for cutaneous wound tissue (normal wound tissue, n = 5; delayed wound tissue, n = 8). (A) Heatmap and (B) volcano plot for cutaneous wound tissue collected 28 days post-injury. (C) Gene expression profiles of normal and delayed cutaneous wound tissue generated by gene ontology (GO) analysis. (D) KEGG pathway analysis showed that the ECM-associated pathway was significantly enriched. Abbreviation: BB, biological process; CC, cellular component; MF, molecular function. All the experiments were repeated at least three times.