Research Paper Volume 12, Issue 8 pp 6990—7005

USP22 promotes development of lung adenocarcinoma through ubiquitination and immunosuppression

Figure 6. Integrated landscape regulation of STAT1 by USP22-KD. (A) Effect of knocking down USP22 on STAT1 signaling pathway. Blue indicates down-regulated expression, while red indicates up-regulated expression. (B) Detection of USP22, UBC and STAT1 by immunohistochemistry in LUAD.