Figure 1. Scheme of the experimental design. (A) Young (2-3 months old) female (n=48) and male (n=48), and old (18-19 months old) female (n=48) and male (n=48) C57BL/6 (B6) mice were fed for 8 weeks on either LFD or HFD. (B) Mice were injured at day 0. Skin tissues were collected at day 0 (uninjured control) and post-wounded days: 3, 7, 14 and 21, n=4-6 mice per time point/per group.