Research Paper Volume 12, Issue 8 pp 7066—7111

Cutaneous wound healing in aged, high fat diet-induced obese female or male C57BL/6 mice

Figure 5. Matrix metalloproteinases and their tissue inhibitor expression during skin wound healing.Mmp-9 (A), Timp-1 (C) and Mmp-13 (D) qRT-PCR mRNA expression in uninjured and post-injured skin tissues collected from female, male, young, old, fed LFD or HFD mice (n=4-8 skin samples per group). Representative Western blot analysis of Mmp-9 protein expression at post-wounded day 3 (B). The bars indicate lsmean ±SE *p<0.05, **p<0.01, ***p<0.001.