Research Paper Volume 12, Issue 8 pp 7183—7206

Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas

Figure 1. Overview of genetic changes in KEAP1 in TCGA–LUAD patients. (A) Bar chart showing the types and numbers of mutations of KEAP1. (B) OnkoKB-predicted mutation maps (lollipop plots) showing the locations of mutations in the functional domains of KEAP1 proteins. The lollipops show the locations of the mutations as identified by whole-exon sequencing.