Research Paper Volume 12, Issue 8 pp 7232—7247

LncRNA XIST promotes myocardial infarction by regulating FOS through targeting miR-101a-3p

Figure 5. XIST regulates myocardial infarction and apoptosis through miR-101a-3p and FOS. (A) Apoptotic cells were analyzed by flow cytometry after anoxia treatment (n=3). (B) Cell viability was detected using the MTT assay. (C) The myocardial infarction size was measured upon MI of mice as determined by 2, 3, 5-triphenyltetrazolium chloride (TTC) staining (n=6). (D) The area at risk/left ventricle weight (AAR/LV) ratio and the infarct size/area at risk (INF/AAR) ratio were determined to evaluate the homogeneity of surgery and the severity of MI, respectively (n=6). Con: control, Adv-sc: Adv-control. Data are shown as mean ± SD, * P<0.05.