Research Paper Volume 12, Issue 8 pp 7248—7261

MicroRNA-375 exacerbates knee osteoarthritis through repressing chondrocyte autophagy by targeting ATG2B

Figure 5. Effects of miR-375 and ATG2B on apoptosis of chondrocytes. (A, B) Effects of miR-375 and ATG2B on apoptosis of chondrocytes was detected by flow cytometry, and the statistical analysis were presented; (C, D) Protein expressions of Bax, Bcl2, cleaved caspase-3 in chondrocytes were measured by western blotting. * P<0.05, ** P<0.01, compared with NC group; # P<0.05, compared with pcDNA3.1-ATG2B group.