Research Paper Volume 12, Issue 8 pp 7334—7349

A novel dipeptide from potato protein hydrolysate augments the effects of exercise training against high-fat diet-induced damages in senescence-accelerated mouse-prone 8 by boosting pAMPK / SIRT1/ PGC-1α/ pFOXO3 pathway

Figure 3. Effect of IF and Exercise on Serum biochemical markers for heart and liver tissue damages. Biochemical analysis after IF administration and 15 weeks of exercise training show the difference in plasma glutamic oxaloacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) levels and serum levels of total cholesterol, Triglycerides, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and blood glucose among the different SAMP8 mice groups (n=6). C: Control; HF: High-fat diet; EX: Exercise; HF+IF: High-fat diet+IF; HF+EX: High-fat diet+ Exercise; HF+EX+IF: High-fat diet+ Exercise+ IF. Bars indicate the mean ± SEM obtained from experiments performed in triplicate. **P<0.01, ***P<0.001 compared with the control group, #P<0.05, ##P<0.01 compared with the HF group.