Research Paper Volume 12, Issue 8 pp 7363—7379

Nudix hydrolase 1 is a prognostic biomarker in hepatocellular carcinoma

Figure 2. NUDT1 protein is overexpressed in HCC tissues. (A) Representative images show immunohistochemical staining results in 95 pairs of HCC and normal liver tissues samples. Normal liver tissues show negative NUDT1 expression, whereas, HCC tissues show negative or low, moderate, and high NUDT1 protein expression as shown. The scale bars indicate 50μm (200x) and 20 μm (400x). (B, C) Kaplan-Meier survival curves show overall survival (OS) and disease-free survival (DFS) curves for HCC patients with high (n=49) and low (n-46) levels of NUDT1 protein expression. (D, E) Kaplan-Meier survival curves show overall survival (OS) and disease-free survival (DFS) curves for HCC patients from the GEPIA database.