Research Paper Volume 12, Issue 8 pp 7363—7379

Nudix hydrolase 1 is a prognostic biomarker in hepatocellular carcinoma

Figure 5. Biological pathways regulated by NUDT1 in HCC cells. (A) GSEA plot shows the key biological pathways regulated by NUDT1 in HCC cells, including fatty acid metabolism (P= 0.0034), cell cycle (P= 0.00112), bile acid and bile salt metabolism (P= 0.00326), and PLK1 pathway (P= 0.00554). (B) The Gene Ontology (GO) enrichment analysis plot shows the biological processes (BP), molecular functions (MF), and cellular components (CC) regulated by NUDT1 in HCC cells. (C) GSEA plot shows enriched signaling and cellular pathways regulated by NUDT1 in HCC cells.