c-Mpl and TPO expression in the human central nervous system neurons inhibits neuronal apoptosis

Liang Li; Chenju Yi; WenJie Xia; Bihui Huang; Shichao Chen; Junyan Zhong; Xiaoyi Fang; Liuming Yang; Hongwu Xin; Shiying Silvia Zheng; Beng H Chong; Yingyun Fu; Chun Chen; Mo Yang

doi:doi:10.18632/aging.103086

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Research Paper Volume 12, Issue 8 pp 7397—7410

c-Mpl and TPO expression in the human central nervous system neurons inhibits neuronal apoptosis

Figure 7. Effect of TPO on Bcl-2 and BAX of C17.2 cells at different time intervals. Cells were stimulated for the selected times with 100 ng/mL of TPO. Bcl-2 and BAX were detected by Western blot. (A) Levels of Bcl-2 and BAX at different time intervals. (B) Semiquantitative evaluation of TPO for antiapoptotic effects via Bcl-2/BAX. * P < 0.05, ** P < 0.01.