Research Paper Volume 12, Issue 8 pp 7448—7464

Overexpression of LINC00160 predicts poor outcome and promotes progression of clear cell renal cell carcinoma

Figure 4. Characteristics of LINC00160 (A) LNCipedia and lncRNAtor websites found LINC00160 with no protein coding ability. (B) lncATLAS website revealed LINC00160 was mainly located in nucleus. (C) Separation of nuclear and cytoplasmic RNA assays indicated that LINC00160 was predominantly localized in nucleus rather than cytoplasm. (D) LINC00160 mRNA expression was significantly higher in RCC cell lines (ACHN, 786-O, Caki-1, OS-RC-2) compared with the kidney control cell line (HK-2). (E) LINC00160 mRNA level was statistically upregulated in tumor samples than adjacent normal tissues.