Research Paper Volume 12, Issue 12 pp 11349—11363

Computational study on new natural compound inhibitors of indoleamine 2,3-dioxygenase 1

Figure 4. Pharmacophore predictions using 3D-QSAR. (A) ZINC000012495022: Green represents hydrogen acceptor, and blue represents hydrophobic center and dark blue represents Ionizable negative. (B) ZINC000003791817: Green represents hydrogen acceptor, blue represents hydrophobic center, purple represents hydrogen donor, and dark blue represents Ionizable negative.