Research Paper Volume 12, Issue 8 pp 7603—7613

LUCS: a high-resolution nucleic acid sequencing tool for accurate long-read analysis of individual DNA molecules

Figure 5. Mutation rates estimated for single molecules from Sanger sequencing and LUCS datasets. Violin plots showing that mutation rates per molecule sequenced, determined by dividing the number of mutations by the coverage of a given molecule, were similar between the two technologies (P = 0.12; see text for details).