Research Paper Volume 12, Issue 12 pp 11398—11415

Immune profiling reveals prognostic genes in high-grade serous ovarian cancer

Figure 6. In vitro assessment of GBP1, ETV7 and CXCL13. (A) The protein levels of GBP1, ETV7 and CXCL13 were measured by western blotting in A2780 cells transfected with siRNAs. (B) CCK-8 assays were performed to evaluate the proliferation of GBP1-, ETV7- and CXCL13-knockdown cells. (C) The colony-forming ability of A2780 cells was assessed to determine the effects of GBP1, ETV7 or CXCL13 downregulation on cell growth. (D) The invasion potential of cells was assessed using a Transwell assay. The scale bar represents 100 μm. NC: negative control. * indicates p< 0.05.