Research Paper Volume 12, Issue 14 pp 14037—14049

Calponin 3 is associated with poor prognosis and regulates proliferation and metastasis in osteosarcoma

Figure 3. CNN3 silencing inhibits osteosarcoma cell proliferation. (A) CNN3 expression in osteosarcoma cell lines and the human osteoblast hFOB 1.19 cell line. (B, C) CNN3 mRNA (B) or protein (C) levels in LV-shCNN3- or LV-NC-infected MG-63 and Saos-2 cells. (D) The proliferation rate (%) of LV-shCNN3- or LV-NC-infected MG-63 and Saos-2 cells at 0, 24, 48, and 72 h. *p<0.05, when LV-shCNN3 vs LV-NC.