Research Paper Volume 12, Issue 12 pp 11466—11484

Androgen receptor affects the response to immune checkpoint therapy by suppressing PD-L1 in hepatocellular carcinoma

Figure 4. The negative correlation between AR and PD-L1 in vivo. (A) AR protein expression and membrane PD-L1 detection in patients’ samples (B) The correlation results between AR and PD-L1 (C) Representative images for scoring the AR IHC staining. (D) Representative images for scoring the PD-L1 IHC staining. (E) Representative images to show the comparison of AR and PD-L1 staining in the same patient. (F) Spearman correlation analysis for AR and PD-L1 based in our stained clinical samples (P value= 0.0039). (G) Survival curve analysis in different AR expression.