Research Paper Volume 12, Issue 11 pp 10337—10358

Altered expression of fibroblast activation protein-α (FAP) in colorectal adenoma-carcinoma sequence and in lymph node and liver metastases

Figure 5. Soluble FAP (sFAP) plasmatic levels in AdC patients (n=127) and in healthy subjects (n=50). (A) sFAP levels were significantly lower in AdC patients than in controls (T Student, p<0.0001). (B) sFAP levels below 30,11 ng/mL were significantly associated with worse overall survival of AdC patients (Log-rank test, p=0.001).