Research Paper Volume 12, Issue 11 pp 10457—10472

Ellagic acid protects mice against sleep deprivation-induced memory impairment and anxiety by inhibiting TLR4 and activating Nrf2

Figure 2. Effect of CL on spatial reference memory in the MWM test in mice. (A) Representative swimming tracks in the MWM during the probe trial. (B) Mean daily escape latencies (time from the start to the hidden platform). (C) Distance travelled during the learning phase of the water maze task. (D) The swimming velocity of the mice. (E) The percentage of time spent in the target quadrant during the probe trial. (F) Frequency of crossing the target quadrant during the probe trials. All values were expressed as the mean ± SEM (n=12), #P < 0.05 and ##P < 0.01 vs. Control group; *P < 0.05 and **P < 0.01 vs. SD group.