Research Paper Volume 12, Issue 11 pp 10129—10146

Clusterin exerts a cytoprotective and antioxidant effect in human osteoarthritic cartilage

Figure 1. Histopathological features of OA articular cartilage. (A) Representative macroscopic images of fractured and OA femoral head samples (left panel) and Haematoxylin&Eosin-stained sections of articular cartilage at low and high magnification (center and right panel). (B) Representative images at different magnification of Alcian blue-PAS staining and (C) alcianophilia in the extracellular matrix of articular cartilage of fractured (n=30 donors; blue bars) and OA patients (n=30 donors; green bars). Abbreviations: A.U., arbitrary units. Mann-Whitney’s U-test: P < 0.0001.