Research Paper Volume 12, Issue 12 pp 11603—11622

Over-expression of microRNA-145 drives alterations in β-adrenergic signaling and attenuates cardiac remodeling in heart failure post myocardial infarction

Figure 1. miR-145 attenuated structural remodeling after HF. (A) relative expression of miR-145 (n=3); (B) quantification of infarcted size (n=5); (C) statistical results of LV fibrosis (n=5); (D) representative imagine of HE and masson’s stain; (E) representative western blots; (FH) quantitative analysis of the immunoreactive band displayed by bar graph (n=3). (a) sham group; (B) HF group; (C) AD-EGFP; (D) AD-miR-145 group; (E) M+C group; IS, infarcted size. Data are presented as mean ± SD.