Research Paper Volume 12, Issue 12 pp 11603—11622

Over-expression of microRNA-145 drives alterations in β-adrenergic signaling and attenuates cardiac remodeling in heart failure post myocardial infarction

Figure 3. MiR-145 depressed the electrophysiological susceptibility of HF. (A) representative MAP recording at a PCL=150ms, APD alternans and PES; (BD) statistical results of APD90, APD alternans threshold and arrhythmia score (n≥5); PCL, pacing cycle length; L, longer APD; S, shorter APD. Data are presented as mean ± SD.