Research Paper Volume 12, Issue 12 pp 11314—11324

Lifelong SIRT-1 overexpression attenuates large artery stiffening with advancing age

Figure 4. Calcified area relative to tunica media area in young, middle-age, and old wild-type (WT) and SIRT-1 transgenic overexpressing (SIRTTG) mice. Figure is accompanied by representative images. Black scale bars are equal to 100 μm. *P<0.05 vs. WT. P<0.05 vs. Young. Data are individual values and means.