Research Paper Volume 12, Issue 12 pp 11314—11324

Lifelong SIRT-1 overexpression attenuates large artery stiffening with advancing age

Figure 5. Aortic SOD1, SOD2, and SOD3 mRNA gene expression in young and old wild-type (WT) and SIRT-1 transgenic overexpressing (SIRTTG) mice (N=5-7/group). *P<0.05 vs. Young WT. †P<0.05 vs. Young SIRTTG. ‡P<0.05 vs. Old WT. Data are mean±SEM normalized to Young WT.