Research Paper Volume 12, Issue 12 pp 11623—11635

Silencing of hsa_circ_0101145 reverses the epithelial-mesenchymal transition in hepatocellular carcinoma via regulation of the miR-548c-3p/LAMC2 axis

Figure 3. Downregulation of hsa_circ_0101145 decreased HCC tumor formation in nude mouse xenografts. (A) Representative images of nude mouse xenografts of HepG2 cells (n = 6). (B) Tumor volumes in mice were measured every 5 days. Data are means ± SD. ***P < 0.001 vs. NC. (C and D) Western blot analysis of the expression of E-cadherin (epithelial marker), and N-cadherin and vimentin (mesenchymal markers). Data are presented as the mean ± SD. ***P < 0.001 vs. NC.