Research Paper Volume 12, Issue 11 pp 11116—11138

Deoxyelephantopin induces apoptosis via oxidative stress and enhances gemcitabine sensitivity in vitro and in vivo through targeting the NF-κB signaling pathway in pancreatic cancer

Figure 4. Effect of DET on apoptosis-related proteins. (A, B) DET activated apoptosis-related proteins in BxPC-3 and CFPAC-1 cells in a concentration dependent manner. Quantitative statistics of immunoblotting analysis for Bax levels (C, D), Bcl-2 levels (E, F), cytochrome c levels (G, H), cleaved caspase-9 levels (I, J), cleaved caspase-3 levels (K, L), *P < 0.05, **P < 0.01 versus CTL. CTL, control.