Research Paper Volume 12, Issue 11 pp 11139—11151

Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases

Figure 2. Melatonin reduced synapse damage in PrP106-126-treated N2a cells. (A, B) Protein expression of PSD95 by Western blotting. (C) Representative images of mitochondria (Original magnification 600×). (D) Quantification of spinophilin. (E) Cells with clustered perinuclear mitochondria *P < 0.05, **P < 0.01. All experiments were repeated at least three times.