Research Paper Volume 12, Issue 12 pp 11698—11716

Epothilone B prevents lipopolysaccharide-induced inflammatory osteolysis through suppressing osteoclastogenesis via STAT3 signaling pathway

Figure 4. Epothilone B suppressed NFATc1 nuclear translocation and the expression of marker genes during osteoclastogenesis. (F) Relative expression of marker genes in the procedure of RANKL or LPS induced osteoclastogenesis on protein level. (G) Quantification of CTSK, MMP9, c-Fos, NFATc1 and CD9 relative to β-actin. Data in the figures represent mean ± SD. N.S. represented no significant difference. *p < 0.05, **p < 0.01, ***p < 0.001 based on one way ANOVA.