Research Paper Volume 12, Issue 12 pp 11717—11731

Resveratrol inhibits the malignant progression of hepatocellular carcinoma via MARCH1-induced regulation of PTEN/AKT signaling

Figure 2. Resveratrol induces HCC cell apoptosis. (A) HepG2 and Hep3B cells were treated with different concentrations of resveratrol for 48 h, followed by analysis of cell apoptosis by flow cytometry. Representative scatter plots are shown. The percentage of apoptosis was calculated. (B) HepG2 and Hep3B cells were seeded in 6-well plates and treated with resveratrol for 24 h, and the medium was changed with fresh medium for 12 days to form colonies. Colonies were fixed and stained. All values represent the mean ± SD. **P < 0.01; *P < 0.05.