Research Paper Volume 12, Issue 12 pp 12019—12031

APOE ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly

Figure 3. Age-related white matter integrity decline. The estimated age trajectories from the linear regression analyses of bilateral cingulum. hippocampus, forceps minor, and right superior longitudinal fasciculus for APOE ε4 carriers (red line) and noncarriers (blue line).