Research Paper Volume 12, Issue 12 pp 12019—12031

APOE ε4 allele accelerates age-related multi-cognitive decline and white matter damage in non-demented elderly

Figure 4. The relationships between white matter integrity and cognitive performance in APOE ε4 carriers. A heatmap reflecting –log (P) values for correlations between white matter integrity and cognitive performance in low-age (26 subjects, <65years) and high-age (27 subjects, ≥65years) ε4 carriers. Though a number of significant correlations were estimated high-age carriers, no correlation was significant in low-age carriers.