Research Paper Volume 12, Issue 12 pp 12032—12050

CD70 contributes to age-associated T cell defects and overwhelming inflammatory responses

Figure 2. CD70 is preferentially expressed on memory CD4+ and CD8+ T cells. Expression of CD70 on each subset (TN, TCM, TEM, and TEMRA) of CD4+ and CD8+ T cells. Representative flow data (A, C) and box plots (B, D) of the percentage of CD70 expression on each subset of CD4+ (AB) and CD8+ (CD) T cells from five different age groups (n = 34-56 in each group). Data are shown as the median ± 95% confidence interval (CI). The p-values were obtained by Kruskal-Wallis test followed by Dunn’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001.