Research Paper Volume 12, Issue 12 pp 12107—12118

MiR-126 promotes esophageal squamous cell carcinoma via inhibition of apoptosis and autophagy

Figure 2. miR-126 silencing suppresses xenograft-induced ESCC tumorigenesis. (A) miR-126 expression in esophageal tissues was measured using qPCR. (B) TE13 cells treated with shRNA-miR-126 or NC were injected subcutaneously into nude BALB/c mice. Mice were sacrificed at day 21 after inoculation, and the tumors were removed and weighed. (C) Tumor growth curve over 27 d. Results are displayed as the average ± SD. *P < 0.05, **P < 0.01, and ***P < 0.001.