Research Paper Volume 12, Issue 12 pp 12142—12159

Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice

Figure 5. Knockdown and overexpression of DIC in hippocampus of APP/PS1 double transgenic mice. (AC) Screening DIC interference sequences (# P>0.05,* P<0.01,versus Control). (DF) Verification of AAVs infection efficiency (# P>0.05,* P<0.01,versus Tg). The data represent as mean ± SEM of a typical series of 3 experiments.