Research Paper Volume 12, Issue 14 pp 14080—14091

CircRNA FGFR3 induces epithelial-mesenchymal transition of ovarian cancer by regulating miR-29a-3p/E2F1 axis

Figure 1. circFGFR3 is overexpressed in OC tissues and is associated with the patients’ poor prognosis. (A) Schematic illustration showing the circularization of MET exons 17 and 18 forming circFGFR3; (B) qRT-PCR were used to detect circFGFR3 expression in OC tissues and adjacent normal tissues, GAPDH served as an internal control. (C) The diagram shows the circFGFR3 expression in OC samples from 35 patients divided into stage I-II and stage III-IV groups, ***P<0.005; (D and E) Kaplan-Meier method was used to analyze the survival and recurrence rates of 35 patients with OC.