Research Paper Volume 12, Issue 12 pp 12175—12186

Combined impact of body mass index and glycemic control on the efficacy of clopidogrel-aspirin therapy in patients with minor stroke or transient ischemic attack

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Figure 1. Comparison of the effect of clopidogrel-aspirin and aspirin alone on clinical outcomes stratified by BMI status and GA levels. Abbreviation: BMI, body mass index; GA, glycated albumin; HR, hazard ratio; CI, confidence interval; Stroke included ischemic stroke and hemorrhagic stroke. Composite events were defined as a new clinical vascular event, including ischemic stroke, hemorrhagic stroke, myocardial infarction, or vascular death. Bleeding was defined as any bleeding event according to the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries criteria. Adjusted variables for HR (95 % CI) were age, sex, NIHSS score at admission, previous or current smoking status, medical history of any ischemic stroke, TIA, myocardial infarction, congestive heart failure, known atrial fibrillation or flutter, valvular heart disease, systolic blood pressure, alanine transaminase, aspartate transaminase, diabetes mellitus, hyperlipidemia, and proton-pump inhibitors.