Research Paper Volume 12, Issue 12 pp 12234—12250

A new risk model comprising genes highly correlated with CD133 identifies different tumor-immune microenvironment subtypes impacting prognosis in hepatocellular carcinoma

Figure 5. Pathway enrichment showing the disturbance of immune hepatic homeostasis. (A) The top gene sets of the hallmark gene sets, curated gene sets, Gene Ontology gene sets, and immunologic signature gene sets. NES>1.5 and FDR<0.25 were used as criteria. (B) The enriched pathways in the hepatic immune microenvironment generated from hallmark gene sets. (C) Highly enriched pathways related to inflammatory responses and the disturbance of immune cells.