Figure 2. Apigenin downregulates CD38 in diabetic rats. (A) Representative photographs of immunohistochemical staining of CD38 in the tubulointerstitial area (scale bar: 100 μm). (B) Western blotting of CD38 and control β-actin in the renal cortex. (C) Densitometric evaluation of the western blotting shown in panel B (n=6). (D) Quantitative RT-PCR of CD38 mRNA normalized to 18S, in the renal cortex (n=6). All data represent the mean ± standard deviation (SD). *p<0.01 vs. other groups.