COVID-19 Research Paper Volume 12, Issue 12 pp 11263—11276

De novo design of protein peptides to block association of the SARS-CoV-2 spike protein with human ACE2

Figure 1. Comparison of the SARS-CoV-2 RBD/hACE2 complex structures (A) and the constructed SARS-CoV-2 RBD/hACE2 peptide complex (B). The superposition of the three complex structures was performed using MM-align [45]; the TM-score [46] between each complex pair was >0.98.