Research Paper Volume 12, Issue 14 pp 14205—14218

Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice

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Figure 4.

The levels of mRNA encoding nAChR α7 (A), α4 (B) and β2 (C) subunits in the hippocampus and cortex of db/db and db/m mouse brains as determined by RT-qPCR. The values presented as percentage of the control by relative quantification are mean ± SEM (n=8 for each group). Application of the two-tailed unpaired Student’s t test revealed no significant differences.