Research Paper Volume 12, Issue 14 pp 14205—14218

Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice

Figure 5. Levels of apoptosis-related protein expressions in the hippocampus and cortex of db/db and db/m mouse brains as determined Western blotting. (A) cleaved caspase-3; (B) Bcl-2; (C) Bax; (D) the Bcl-2/Bax ratio. The values presented as percentage of the control by relative quantification are mean ± SEM (n=8 for each group). *p<0.05 as compared to db/m mice as determined by the two-tailed unpaired Student’s t test. Representative Western blots are displayed in the upper left corner of the figure.