Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and <i>db/db</i> mice

Yi Xu; Kun Cao; Bing Guo; Jie Xiang; Yang-Ting Dong; Xiao-Lan Qi; Wen-Feng Yu; Yan Xiao; Zhi-Zhong Guan

doi:doi:10.18632/aging.103435

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Research Paper Volume 12, Issue 14 pp 14205—14218

Lowered levels of nicotinic acetylcholine receptors and elevated apoptosis in the hippocampus of brains from patients with type 2 diabetes mellitus and db/db mice

Figure 8. Correlation between nAChR subunits and Bcl-2/Bax ratio, Syn or Snap-25 in the hippocampus of db/db mouse brains. (A1–3) the correlation between α7 and Bcl-2/Bax, Syn or Snap-25; (B1–3) the correlation between α4 and Bcl-2/Bax, Syn or Snap-25. The values presented are mean ± SEM (n=8) as determined with the Pearson correlation test.