Research Paper Volume 12, Issue 14 pp 14285—14299

C5aR deficiency attenuates the breast cancer development via the p38/p21 axis

Figure 1. Enhanced C5aR expression in tumoral tissues of patients with BC. C5aR expression in BC tumoral tissues (T) and BC-adjacent non-tumoral tissues (N) was detected by (A) immunochemistry and (B) western blotting. (C) C5a and (D) C5 levels in serum were measured by enzyme-linked immunosorbent assay (ELISA) (healthy volunteers, n=20; BC patients, n=27). Magnification: 200×. The data are representative of three independent experiments. Data are presented as means ± SD. ***P<0.001.