Research Paper Volume 12, Issue 14 pp 14314—14328

Circular RNA-9119 suppresses in ovarian cancer cell viability via targeting the microRNA-21-5p–PTEN–Akt pathway

Figure 2. circ9119 decreased cell viability of ES-2 and SKOV-3 cells. The cells were transfected with circ9119 overexpression or NC vector for 1.5 d. (A, B) qRT–PCR examined the circ9119expression. (C, D) MTT assay showed the proliferation rate of ES-2 and SKOV-3 cells at 12–48 h post transfection. (E, F) Soft agar colony formation assay conducted in SKOV-3 and ES-2 cells with circ9119 overexpression at 48 h post transfection. n = 3. *P < 0.05, **P < 0.01, ***P < 0.001 vs. the NC groups.